Medicines for Mankind

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Disease: Multiple Sclerosis

Last update: June 2008

Intro

Multiple sclerosis is a disease of the central nervous system. The insulating sheath around the nerves is progressively destroyed. This leads to a variety of distressing symptoms. It typically affects young adults. The cause is still unknown. New approaches to treatment are being tested including antibody therapies and a factor that may help nerve regeneration. Hopefully, future therapies for this devastating disease will be more than just palliative.

FAQ: What can be done about it?

Anti-inflammatory steroids have a role in reducing the duration and severity of acute attacks. Medicines which relax the muscles may be given to reduce muscle spasms. Other drugs are used to treat incontinence.

Newer treatments include forms of a protein called beta-interferon which has shown clinical benefits. Another development has been a drug which is thought to mimic part of the myelin sheath.