Medicines for Mankind

Today's reasearch, Tomorrows's Cures

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Disease: Fungal infections

Last update: June 2008

Intro

Fungal infections can be mild or life-threatening. They can pose a serious risk to people with a compromised immune system. Some infections are becoming resistant to current treatments. New compounds are being developed that are active against a range of fungi, including resistant strains. The aim is to reduce deaths from overwhelming fungal infection.

FAQ: What does the future hold?

New azole compounds are being developed that are active against a range of fungi, including resistant strains. Also being researched is an entirely new class of antifungals that block the production of a major component of the fungal cell wall, killing the fungus rather than just stopping it growing. Recently another class of substances has been identified which block the production of a particular protein.

Just as with antibacterial agents, research needs to continue to overcome the challenge posed by resistance.